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The Thyroid Gland01:23

The Thyroid Gland

6.1K
The thyroid gland is a small, butterfly-shaped gland located in the neck and covers the anterior surface of the trachea. The gland has two lateral lobes connected by a thin tissue mass called the isthmus. Internally, each lobe comprises many small spherical structures known as thyroid follicles, surrounded by a network of blood vessels.
The follicles have a central cavity lined by simple cuboidal to squamous epithelial cells called follicular cells. These cells produce the glycoprotein...
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Synthesis and Regulation of Thyroid Hormones01:20

Synthesis and Regulation of Thyroid Hormones

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Low blood levels of the thyroid hormones — triiodothyronine (T3) and thyroxine (T4) — signal the hypothalamus to release the thyrotropin-releasing hormone (TRH). TRH then reaches the pituitary gland and stimulates the release of thyroid-stimulating hormone(TSH) into the bloodstream.
Upon reaching the thyroid gland, TSH stimulates the follicular cells' active uptake of iodide ions from the blood. The ions diffuse to the apical surface of the cells and are oxidized to iodine. The...
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The Hyoid Bone01:12

The Hyoid Bone

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The hyoid bone is a small U-shaped bone located in the upper neck at the level of the inferior mandible, with its tips pointing posteriorly. It does not directly articulate with any other bone in the body. The hyoid acts as the attachment site for the tongue, the larynx, and the pharynx. It is held in position by a series of small muscles attached from above or below. These muscles help to move the hyoid up/down or forward/back in coordination with movements of the tongue, larynx, and pharynx...
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Larynx01:21

Larynx

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The human larynx, often referred to as the voice box, is an intricate organ located in the neck. It serves as a pathway for air to enter the lungs during respiration and is an essential component of voice production.
Anatomy of the Larynx
The larynx consists of various components, including cartilage, muscles, and vocal cords. Its structure includes three large unpaired cartilages—the thyroid, cricoid, and epiglottis—and three smaller paired cartilages—the arytenoids,...
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Cardiopulmonary Resuscitation II: ACLS Airway Management01:22

Cardiopulmonary Resuscitation II: ACLS Airway Management

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Airway management is a key skill in emergency and critical care settings, as maintaining a clear airway is essential for adequate oxygenation and ventilation.Head Tilt-Chin Lift TechniqueThe head tilt-chin lift maneuver is an essential technique primarily used in patients without suspected cervical spine injuries. To perform this maneuver, one hand is placed on the patient’s forehead, and gentle pressure is applied backward to tilt the head. The fingertips of the other hand are positioned...
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Tongue01:01

Tongue

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The human tongue is a fascinating and complex organ, responsible for various essential functions such as swallowing, speech, and taste. It is also subject to various conditions and diseases. In this article, we delve into the anatomy of the tongue, its roles, and some common conditions that can affect it.
Anatomical Position in the Oral Cavity
The tongue is located within the oral cavity, also known as the mouth. It is attached to the floor of the mouth by a fold of mucous membrane called the...
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Related Experiment Video

Updated: Dec 4, 2025

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy
05:12

Transoral Endoscopic Thyroidectomy Vestibular Approach for Thyroid Lobectomy

Published on: May 12, 2023

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Obstructive lingual thyroid.

Mario E Gonzalez1

  • 1Department of Otolaryngology Head and Neck Surgery University of Puerto Rico School of Medicine San Juan Puerto Rico.

Clinical Case Reports
|October 22, 2020
PubMed
Summary
This summary is machine-generated.

Lingual thyroid is a rare condition that can present as a neck mass. Most patients with lingual thyroid are hypothyroid and improve with hormone therapy, with surgery reserved for severe cases.

Keywords:
dysphagiahypothyroidismlingualobstructivethyroidtongue

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Area of Science:

  • Endocrinology
  • Otolaryngology
  • Head and Neck Surgery

Background:

  • Lingual thyroid is a congenital anomaly resulting from aberrant thyroid tissue migration.
  • It presents as a mass at the base of the tongue, potentially causing airway obstruction.

Purpose of the Study:

  • To review the clinical presentation, diagnostic considerations, and management strategies for lingual thyroid.
  • To emphasize the importance of considering lingual thyroid in the differential diagnosis of base of tongue masses.

Main Methods:

  • Review of existing literature on lingual thyroid.
  • Analysis of clinical cases presenting with base of tongue masses and confirmed lingual thyroid.

Main Results:

  • Lingual thyroid is often associated with hypothyroidism, with a majority of patients responding to thyroid hormone replacement therapy.
  • Surgical intervention is typically reserved for cases unresponsive to medical management or those with significant obstructive symptoms.

Conclusions:

  • Lingual thyroid requires consideration in the differential diagnosis of base of tongue masses.
  • Hormone replacement therapy is the primary treatment, with surgery indicated only in specific circumstances.