Related Experiment Video
Updated: Dec 4, 2025

Minimally Invasive Murine Laryngoscopy for Close-Up Imaging of Laryngeal Motion During Breathing and Swallowing
Published on: December 1, 2023
Screening Test for LPRD: History Versus Video Laryngoscopy
Prasun Mishra1, Deeksha Agrawal1, Purva Artham1
1Department of ENT, Bharati Vidyapeeth Deemed to be University and Medical College, Pune, Maharashtra 411043 India.
This study found no significant correlation between the Reflux Symptom Index (RSI) and Reflux Finding Score (RFS) for diagnosing laryngopharyngeal reflux disease (LPRD). Both screening tools are recommended for LPRD diagnosis.
Area of Science:
- Otolaryngology
- Gastroenterology
- Diagnostic Medicine
Background:
- Laryngopharyngeal reflux disease (LPRD) presents diagnostic challenges.
- Current screening methods include patient history (Reflux Symptom Index - RSI) and objective examination (Reflux Finding Score - RFS via video-laryngoscopy).
- Optimizing diagnostic accuracy for LPRD is crucial for effective patient management.
Purpose of the Study:
- To evaluate the correlation between the Reflux Symptom Index (RSI) and the Reflux Finding Score (RFS) in patients with suspected LPRD.
- To determine if RSI and RFS can be used as reliable, standalone screening tools for LPRD.
- To identify the most prevalent symptoms and findings associated with LPRD.
Main Methods:
- Patients with LPRD signs/symptoms were assessed using the RSI.
- Individuals with an RSI > 13 underwent video-laryngoscopy and RFS evaluation.
- Statistical analysis was performed to correlate RSI and RFS scores.
Main Results:
- 107 patients were included; 55% were female, with a mean age in the middle group.
- A positive RFS score (>7) was observed in 58.3% of patients.
- The mean RSI was 18.22 and the mean RFS was 7.45. Heartburn/indigestion was the most common symptom (44.5%), and posterior commissure hypertrophy was the most common finding (95%).
- A non-significant correlation (r=0.184, p=0.159) was found between RSI and RFS.
Conclusions:
- LPRD is more prevalent in females and the middle-aged population.
- The lack of significant correlation suggests that neither RSI nor RFS alone is sufficient for LPRD diagnosis.
- Utilizing both RSI and RFS as complementary, outpatient-based screening tools enhances diagnostic reliability for LPRD.
Related Concept Videos
Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques
Endoscopic Studies I: Bronchoscopy and Thoracoscopy
Bronchoscopy
Description
Bronchoscopy is a procedure that involves direct visualization of the larynx, trachea, and bronchi for diagnostic and therapeutic purposes. A flexible fiber optic or rigid bronchoscope is used to carry out the procedure. The fiber-optic bronchoscope is more frequently used due...
Physical Assessment of the Respiratory Tract I: Health History
Subjective Data
Subjective data provides vital information about the patient's health history and symptoms. This data is typically collected through interviews in which patients describe their experiences, symptoms, and concerns.
Health history and...
Endoscopic Procedures I: Esophagogastroduodenoscopy
During an EGD, the endoscope can be used to:

