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Published on: February 26, 2013
Atrial fibrillation: a risk factor for unfavourable outcome in COVID-19? A case report
Sebastian Schnaubelt1, Marie-Kathrin Breyer2, Jolanta Siller-Matula3,4
1Department of Emergency Medicine, Medical University of Vienna, Vienna, Austria.
Insights
COVID-19 can cause severe heart problems, especially in older adults with atrial fibrillation. Managing heart failure in these patients requires controlling heart rate and rhythm, and possibly immunomodulation.
Area of Science:
- Cardiology
- Infectious Diseases
- Critical Care Medicine
Background:
- COVID-19 is associated with cardiac complications like myocarditis, arrhythmias, and pericardial tamponade.
- Atrial fibrillation is prevalent in elderly individuals, a demographic highly susceptible to severe COVID-19 outcomes.
- Understanding the interplay between COVID-19 and pre-existing cardiac conditions is crucial.
Observation:
- A 72-year-old male with SARS-CoV-2 presented with delirium and acute respiratory failure.
- His pre-existing atrial fibrillation worsened, necessitating complex rate and rhythm management.
- The patient developed progressive heart failure, hemodynamic instability, acute kidney injury, and pericardial tamponade.
Findings:
- Fulminant cardiac involvement in COVID-19 can be exacerbated by pre-existing conditions such as atrial fibrillation.
- The cytokine storm in severe COVID-19 can precipitate hemodynamic deterioration and multi-organ dysfunction.
- Pericardial tamponade is a critical complication that can arise in severe COVID-19 with cardiac compromise.
Implications:
- Effective management of COVID-19 cardiac complications requires addressing both the viral infection and underlying cardiac conditions.
- Rate or rhythm control is essential for managing tachycardic atrial fibrillation in critically ill COVID-19 patients.
- Immunomodulatory therapies may play a role in mitigating the cytokine storm and improving outcomes in severe COVID-19 with cardiac involvement.
Background:
Fulminant cardiac involvement in COVID-19 patients has been reported; the underlying suspected mechanisms include myocarditis, arrhythmia, and cardiac tamponade. In parallel, atrial fibrillation is common in the elderly population which is at particularly high risk for COVID-19 morbidity and mortality.
Case Summary:
A 72-year-old male SARS-CoV2-positive patient was admitted to the intensive care unit due to delirium and acute respiratory failure. Atrial fibrillation known from history was exacerbated, and made complex rate and rhythm control necessary. Progressive heart failure with haemodynamic deterioration and acute kidney injury with the need for continuous renal replacement therapy were further aggravated by pericardial tamponade.
Discussion:
Treatment of acute heart failure in COVID-19 patients with a cytokine storm complicated by tachycardic atrial fibrillation should include adequate rate or rhythm control, and potentially immunomodulation.
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