Related Experiment Video
Updated: Dec 4, 2025
03:10
Author Spotlight: Development and Evaluation of a Compound Acne Rodent Model Using C. acnes and Oleic Acid
Published on: November 1, 2024
3.3K
Sub-classification of Hidradenitis suppurativa: a cross-sectional study
Linnea Thorlacius1,2, Peter T Riis3, Emil Knudsen List3
1Department of Dermatology, Roskilde; Health Sciences Faculty, Zealand University Hospital, University of Copenhagen, Sygehusvej 10, 4000, Roskilde, Denmark. linneath@gmail.com.
Archives of Dermatological Research
|October 22, 2020
Summary
Researchers identified two Hidradenitis Suppurativa (HS) subtypes based on flare locations: an "upper type" affecting the chest and armpits, and a "lower type" affecting the groin and buttocks.
Area of Science:
- Dermatology
- Medical Subspecialties
Background:
- Hidradenitis Suppurativa (HS) presents a broad spectrum of disease, lacking established sub-classifications.
- Current understanding suggests potential differences in treatment response and prognosis among HS subtypes.
Purpose of the Study:
- To develop an empirical framework for sub-classifying Hidradenitis Suppurativa (HS) patients.
- To identify HS subtypes based on the frequency and anatomic distribution of disease flares.
Main Methods:
- Cross-sectional, questionnaire-based study involving 524 patients with confirmed HS.
- Utilized Principal Component Analysis (PCA) and cluster analysis to identify patient subgroups based on flare locations.
Main Results:
- Identified two distinct HS subtypes: 'upper type' (axillary, mammary flares) and 'lower type' (inguinal, genital, perianal, gluteal flares).
- The study included 76.7% female participants, reflecting typical HS demographics.
Conclusions:
- Findings support the potential for sub-classifying Hidradenitis Suppurativa (HS).
- Anatomic location of flares may serve as a crucial factor in future HS classification systems.
