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Cannabidiol interactions with voltage-gated sodium channels.

Lily Goodyer Sait1, Altin Sula1, Mohammad-Reza Ghovanloo2

  • 1Institute of Structural and Molecular Biology, Birkbeck College, University of London, London, United Kingdom.

Elife
|October 22, 2020
PubMed
Summary

Cannabidiol (CBD) interacts with voltage-gated sodium channels at a unique site, blocking ion flow. This discovery offers a molecular explanation for CBD

Keywords:
cannabidiolcrystal structuredrug interationselectrophysiologymolecular biophysicsnonestructural biologystructure-function relationshipsvoltage -gated sodium channel

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