Related Experiment Video
Updated: Dec 4, 2025

A Method of Trigonometric Modelling of Seasonal Variation Demonstrated with Multiple Sclerosis Relapse Data
Published on: December 9, 2015
Comparison of ofatumumab and other disease-modifying therapies for relapsing multiple sclerosis: a network
Imtiaz A Samjoo1, Evelyn Worthington1, Christopher Drudge1
1EVERSANA™, 204-3228 South Service Road, Burlington, Ontario L7N 3H8, Canada.
Abstract:
Aim: To compare the efficacy of ofatumumab to other disease-modifying therapies (DMTs) for relapsing multiple sclerosis (RMS). Materials & methods: A network meta-analysis was conducted to determine the relative effect of ofatumumab on annualized relapse rate and confirmed disability progression at 3 months and 6 months. Results: For each outcome, ofatumumab was as effective as other highly efficacious monoclonal antibody DMTs (i.e., alemtuzumab, natalizumab and ocrelizumab). Conclusion: Ofatumumab offers beneficial outcomes for RMS by reducing relapse and disability progression risk.
Related Concept Videos
Drugs for Treatment of Crohn's Disease in IBD Using Biologic Agents: Anti-TNF
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
Therapeutic Drug Monitoring: Overview and Classification
Pharmaceutical Alternatives: Polymorphic Form-Related and Particle Size-Related Therapeutic Nonequivalence
Therapeutic Drug Monitoring: Affecting Factors
Bioequivalence of Drugs: Drugs with Multiple Indications

