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    Area of Science:

    • Biomedical Engineering
    • Cardiovascular Monitoring
    • Wearable Technology

    Background:

    • Optimizing peri-operative fluid management is crucial for patient outcomes.
    • Stroke volume (SV) measurement guides fluid therapy, but current methods like Transesophageal Doppler (TED) are limited to intra-operative use.
    • Continuous, non-invasive SV monitoring is lacking for both intra- and post-operative care.

    Purpose of the Study:

    • To propose and evaluate a wearable patch for continuous, non-invasive stroke volume (SV) prediction.
    • To assess the feasibility of using seismocardiogram (SCG) and electrocardiogram (ECG) signals for SV monitoring.
    • To provide an alternative to the Transesophageal Doppler (TED) for peri-operative fluid management.

    Main Methods:

    • A wearable patch capturing seismocardiogram (SCG) and electrocardiogram (ECG) signals was developed.
    • Hemodynamic data, including SV, were recorded simultaneously using the wearable patch and Transesophageal Doppler (TED) in 12 patients.
    • Signal processing and regression techniques were applied to derive SV from the wearable patch signals.

    Main Results:

    • The combination of SCG and ECG signals effectively predicted stroke volume (SV).
    • A correlation of 0.81 was achieved between predicted and reference SV values.
    • A median absolute error of 7.56 mL was observed, demonstrating accuracy.

    Conclusions:

    • The proposed wearable patch shows significant promise for continuous, non-invasive stroke volume monitoring.
    • This technology can serve as a viable alternative to the Transesophageal Doppler (TED).
    • It facilitates improved peri-operative fluid management through real-time patient data.