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Glutamine degradation through the omega-amidase pathway in Saccharomyces cerevisiae
1Centro de Investigación sobre Fijación de Nitrógeno, UNAM, Cuernavaca, Morelos.
Journal of General Microbiology
|January 1, 1987
Abstract:
A glutamine transaminase activity has been identified in Saccharomyces cerevisiae, and the existence of the omega-amidase activity previously described in this yeast has been confirmed. The glutamine transaminase utilizes different 2-oxo acids as substrates, including pyruvate and glyoxylate, and is regulated by the available nitrogen source. The glutamine transaminase activity decreases when lysine or glycine is added to the medium; the inhibition by lysine diminishes under microaerophilic culture conditions.