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Updated: Dec 4, 2025

Testing Sensory and Multisensory Function in Children with Autism Spectrum Disorder
Published on: April 22, 2015
Impaired inhibitory processing: a new therapeutic target for autism and psychosis?
Kareen Heinze1, Helen C Barron2, Emma K Howes3
1School of Psychology, University of Birmingham; and Institute for Mental Health, University of Birmingham; and Centre for Human Brain Health, University of Birmingham, Edgbaston, UK.
Abstract:
In the healthy brain, homeostatic balance between excitation and inhibition maintains neural stability. Reduced inhibition may explain shared symptoms observed in autism and psychosis. Here we review evidence suggesting that altered levels of gamma-aminobutyric acid (GABA) may underlie both disorders, providing a potential cross-diagnostic therapeutic target.
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