Related Experiment Video
Updated: Dec 4, 2025

Author Spotlight: Enhancing Coronary Artery Revascularization
Published on: September 15, 2023
Perioperative Extracorporeal Membrane Oxygenation for Refractory Cardiopulmonary Failure Complicating Papillary
Roberto Pinto1, Raquel Maia2, Paulo Pinho3
1Department of Cardiology, Centro Hospitalar S. João, Porto, Portugal; Department of Biomedicine, Faculty of Medicine of Porto, Porto, Portugal.
Abstract:
The prognosis of papillary muscle rupture (PMR) leading to acute mitral regurgitation, pulmonary oedema, and cardiogenic shock remains dismal, with survival dependent on prompt recognition and surgical intervention. The use of extracorporeal membrane oxygenation (ECMO) for circulatory and/or respiratory support in critically ill patients failing conventional treatment has significantly increased in the past few years, mainly owing to technology improvements that have rendered the provision of this technique simpler and safer. In this report, four cases of refractory cardiopulmonary collapse complicating ischaemic and traumatic PMR successfully managed perioperatively with ECMO are presented. In this context, a review of the potential role of perioperative ECMO support for cardiogenic shock secondary to cardiac mechanical complications is also provided.
Insights
Papillary muscle rupture (PMR) causing severe heart problems has a poor outlook. Extracorporeal membrane oxygenation (ECMO) offers a life-saving perioperative support option for these critically ill patients.
Area of Science:
- Cardiology
- Cardiothoracic Surgery
- Critical Care Medicine
Background:
- Papillary muscle rupture (PMR) is a severe complication leading to acute mitral regurgitation, pulmonary edema, and cardiogenic shock, often with a dismal prognosis.
- Conventional treatments for refractory cardiopulmonary collapse secondary to PMR have limited success.
- Extracorporporeal membrane oxygenation (ECMO) has emerged as a crucial support modality due to technological advancements.
Observation:
- This report details four cases of refractory cardiopulmonary collapse due to ischemic and traumatic PMR.
- These patients were successfully managed with perioperative ECMO support.
- The study reviews the utility of ECMO in managing cardiogenic shock from cardiac mechanical complications.
Findings:
- Perioperative ECMO can be successfully employed in managing refractory cardiopulmonary collapse secondary to papillary muscle rupture.
- ECMO provides vital circulatory and/or respiratory support in critically ill patients who fail conventional therapies.
- Prompt recognition and intervention, including ECMO, are critical for survival in PMR.
Implications:
- Perioperative ECMO represents a viable and potentially life-saving strategy for patients with severe papillary muscle rupture and cardiogenic shock.
- The findings support the expanded use of ECMO in managing complex cardiac mechanical complications.
- Further research into optimizing ECMO protocols for PMR patients is warranted.
More Related Videos
Related Concept Videos
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Cardiopulmonary Resuscitation IV: Pharmacological Management
Cardiopulmonary Resuscitation II: ACLS Airway Management
Acute Respiratory Failure-III
Acute Respiratory Failure-IV

