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Elevated Plus Maze Test Combined with Video Tracking Software to Investigate the Anxiolytic Effect of Exogenous Ketogenic Supplements
Published on: January 7, 2019
Perspective: Ketone Supplementation in Sports-Does It Work?
Pedro L Valenzuela1, Adrián Castillo-García2, Javier S Morales3
1Department of Systems Biology, University of Alcalá, Madrid, Spain.
Oral ketone supplements show limited evidence for improving sports performance or cognition. Current research suggests potential gastrointestinal side effects, and more studies are needed on long-term safety and effectiveness.
Area of Science:
- Sports Science
- Nutritional Biochemistry
- Exercise Physiology
Background:
- Oral ketone supplements are increasingly popular for potential performance enhancement.
- Theoretical benefits include altered muscle fuel utilization, improved cognition, and enhanced glycogen synthesis.
Purpose of the Study:
- To evaluate the current evidence for the ergogenic and cognitive effects of oral ketone supplementation.
- To assess the safety and efficacy of ketone supplements in sports and exercise contexts.
Main Methods:
- Review of existing scientific literature and research perspectives on ketone supplementation.
- Analysis of studies investigating acute and chronic effects on performance, cognition, and recovery.
Main Results:
- Current evidence does not support acute ketone supplementation for improving sports performance, cognition, or muscle recovery.
- Further research is required for long-duration exercise (>60 minutes) and chronic supplementation protocols.
- Acute intake may cause gastrointestinal distress; long-term safety data is lacking.
Conclusions:
- Insufficient evidence currently supports the overall effectiveness of ketone supplements in sports.
- More research is needed to determine the efficacy and safety of ketone supplements for athletes.
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