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Related Concept Videos

Sleep Apnea01:21

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Sleep apnea is a condition where breathing stops intermittently during sleep, often leading to significant health issues. Each episode can last from 10 to 20 seconds or more and is frequently accompanied by a brief arousal from sleep. This disturbance, largely unnoticed by the individual, can lead to severe daytime fatigue. Commonly, individuals seek help after being informed by their partners about loud snoring and noticeable breathing pauses during sleep.
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Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
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In anatomy, several standard anatomical positions are used as references for describing the position and orientation of different body parts. These positions help provide a common frame of reference when discussing anatomical structures. The anatomical position is the standard reference point for describing the body's position and orientation. In this position:
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Drug-Induced Sleep Endoscopy DISE with Target Controlled Infusion TCI and Bispectral Analysis in Obstructive Sleep Apnea
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Persistent OSA in obese children: does body position matter?

Kaitlyn Tholen1,2, Maxene Meier3, Jackson Kloor4

  • 1Department of Pediatric Otolaryngology, University of Colorado School of Medicine, Aurora, Colorado.

Journal of Clinical Sleep Medicine : JCSM : Official Publication of the American Academy of Sleep Medicine
|October 23, 2020
PubMed
Summary

Positional therapy may be an effective treatment for obese children with obstructive sleep apnea (OSA). Sleeping in a nonsupine position significantly increased the likelihood of cure compared to supine sleep.

Keywords:
childobesityobstructive sleep apneapolysomnogrampositional obstructive sleep apneasleep positionsleep studytonsillectomy

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Area of Science:

  • Pediatric Sleep Medicine
  • Otolaryngology
  • Obesity Research

Background:

  • Obstructive sleep apnea (OSA) is a common condition in obese children.
  • Persistent OSA after adenotonsillectomy poses a challenge in this population.
  • Positional therapy is a potential non-invasive treatment approach.

Purpose of the Study:

  • To evaluate the efficacy of positional therapy as a treatment for obese children with persistent OSA.
  • To compare sleep apnea severity based on sleep position in children post-adenotonsillectomy.

Main Methods:

  • Retrospective review of 154 obese children (BMI ≥ 95th percentile) with OSA post-adenotonsillectomy.
  • Categorization based on sleep position: mixed, nonsupine, or supine sleep.
  • Analysis of OSA/apnea-hypopnea index (AHI) and cure rates (AHI < 1 event/h) using t-tests and McNemar's test.

Main Results:

  • Supine sleep position showed a significantly higher average AHI (7.9 events) compared to nonsupine sleep (4.1 events) in children with mixed sleep (P < .01).
  • Children sleeping predominantly in a nonsupine position were significantly more likely to achieve cure (P < .001).

Conclusions:

  • Positional therapy is a viable treatment alternative for obese children with persistent OSA.
  • Sleep position significantly impacts OSA severity and treatment outcomes.
  • Postoperative polysomnography should consider sleep position for accurate assessment.