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[In situ hybridization in molecular pathological diagnostics]

Hans-Ulrich Schildhaus1

  • 1Institut für Pathologie, Universitätsklinikum Essen, Hufelandstraße 55, 45147, Essen, Deutschland. hans-ulrich.schildhaus@uk-essen.de.

Der Pathologe
|October 23, 2020
PubMed
Summary

No abstract available in PubMed .

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In situ hybridization (ISH) is a technique used to detect and localize specific DNA or RNA molecules in cells, tissue, or tissue sections using a labeled probe. The technique was first used in 1969 for the investigation of nucleic acids. It is currently an essential tool in scientific research and clinical settings, especially for diagnostic purposes.
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