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Updated: Dec 4, 2025
Nerve Ultrasound Protocol to Detect Dysimmune Neuropathies
Published on: October 7, 2021
[Informative value of ultrasound in the diagnosis of intraneural perineurioma]
D S Druzhinin1,2, E S Druzhinina2, M L Novikov3
1Yaroslavl State Medical University, Yaroslavl, Russia.
Objective:
To describe clinical and sonographic features of confirmed intraneural perineurioma in 5 patients.
Material And Methods:
We report clinical and sonographic features and retrospective follow-up data in 5 patients with intraneural perineurioma verified by biopsy.
Results:
In all cases, symptoms were represented by a slowly progressive painless mononeuropathy with muscle atrophy and impaired tendon reflexes. Ultrasound examination revealed locally enlarged cross-sectional area of the nerve that was confirmed by intraoperative visualization.
Conclusion:
Intraneural perineurioma should be obligatory suspected in case of fusiform thickening of the nerve with locally changed echogenicity. Pooled multiple-center studies with large samples are needed to determine sensitivity and specificity of the main ultrasound parameters including changes in cross-sectional area and echogenicity of the nerve.
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