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Database resources of the National Center for Biotechnology Information
Eric W Sayers1, Jeffrey Beck1, Evan E Bolton1
1National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Building 38A, 8600 Rockville Pike, Bethesda, MD 20894, USA.
Nucleic Acids Research
|October 23, 2020
Summary
The National Center for Biotechnology Information (NCBI) offers extensive online biological data resources, including GenBank and PubMed. Recent updates enhance access to these vital life science tools.
Area of Science:
- Biotechnology
- Bioinformatics
- Genomic Data Management
Background:
- The National Center for Biotechnology Information (NCBI) is a key resource for biological data.
- It hosts major databases like GenBank and PubMed, crucial for life science research.
- The Entrez system facilitates data retrieval across 34 distinct databases.
Purpose of the Study:
- To provide an overview of the NCBI's comprehensive online resources for biological information and data.
- To highlight recent updates and improvements to NCBI's platforms and databases.
- To inform users about accessing and utilizing these essential scientific tools.
Main Methods:
- Utilizing the Entrez system for search and retrieval operations across multiple NCBI databases.
- Employing custom BLAST program implementations for sequence-based searching.
- Accessing resources via the NCBI homepage and E-utilities programming interface.
Main Results:
- NCBI provides access to 34 distinct databases through the Entrez system.
- New resources include an updated PubMed interface and NCBI datasets.
- Numerous existing resources such as PMC, Bookshelf, and ClinVar have been updated.
Conclusions:
- NCBI offers a robust and expanding suite of resources for biological research.
- Continuous updates ensure users have access to the latest data and improved functionalities.
- All resources are readily accessible via the NCBI website, supporting global scientific endeavors.
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