Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Esophageal Strictures-I: Introduction01:30

Esophageal Strictures-I: Introduction

425
Esophageal strictures involve abnormal narrowing or tightening of the esophagus. They vary in length and severity, ranging from mild constriction to complete obstruction, and are classified as benign (noncancerous) or malignant (cancerous).
Etiology
The primary cause of esophageal strictures is long-standing gastroesophageal reflux disease (GERD), accounting for about 70 to 80% of adult cases. Chronic acid reflux can lead to injury and scarring of the esophageal lining, culminating in...
425
Barrett Esophagus-I: Introduction01:21

Barrett Esophagus-I: Introduction

402
Barrett's esophagus is a medical condition where the esophageal mucosa is significantly damaged by stomach acid or other digestive fluids, often due to long-term exposure associated with gastroesophageal reflux disease (GERD). In GERD, a weakened or abnormally relaxed lower esophageal sphincter allows stomach acid to flow persistently into the esophagus.
This constant acid exposure transforms the esophagus's pink mucosal lining (stratified squamous epithelium) into a type of lining more...
402
Barrett Esophagus-II: Clinical Manifestations and Management01:21

Barrett Esophagus-II: Clinical Manifestations and Management

534
Individuals with Barrett's esophagus are often asymptomatic, but they may experience symptoms commonly associated with GERD, such as heartburn and acid regurgitation. Additional symptoms can include difficulty swallowing, chest pain, unintentional weight loss, blood in the stool (which may appear black, tarry, or bloody), and episodes of vomiting.
To diagnose Barrett's esophagus, healthcare providers often recommend an endoscopy for those showing symptoms of acid reflux. The procedure...
534
Esophageal Varices-I: Introduction01:24

Esophageal Varices-I: Introduction

823
Esophageal varices are dilated, tortuous veins which are found mainly in the submucosa of the lower esophagus but which may also appear higher up or extend into the stomach. They develop due to increased pressure in the portal venous system, often as a result of liver cirrhosis. This condition scars and damages the liver, impeding normal blood flow through the portal vein. To compensate, blood seeks alternative pathways, forming fragile new vessels (varices) in the esophagus and stomach. These...
823
Esophagus01:24

Esophagus

3.2K
The esophagus, a muscular conduit linking the pharynx and stomach, measures roughly 10 inches (25.4 cm) and sits behind the trachea. It remains collapsed when not swallowing. The esophagus follows a predominantly straight path through the thoracic mediastinum and enters the abdominal cavity through a diaphragmatic opening known as the esophageal hiatus.
The movement of edibles from the pharynx into the esophagus is facilitated by the upper esophageal sphincter, which is formed primarily by the...
3.2K
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

265
Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
265

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Feasibility of Post-Operative Telehealth for Pediatric Surgical Patients in Malawi-A Mixed Methods Analysis.

World journal of surgery·2026
Same author

Disparities in Depression Among Older Asian, Native Hawaiian, and Pacific Islander Patients With Lung Cancer.

Cancer medicine·2026
Same author

Strategies for optimizing clinical trial recruitment: perspectives among patients with breast cancer.

Cancer causes & control : CCC·2026
Same author

Longitudinal multimodal assessment of neuropathy in a porcine neuritis model.

Journal of neuroscience methods·2026
Same author

Breast Health Training Program for Traditional Healers: A Pathway to Early Breast Cancer Detection in Tanzania.

Cancer reports (Hoboken, N.J.)·2026
Same author

Factors Contributing to Late Breast Cancer Diagnosis: A Qualitative Study on the Patient's Perspective in Tanzania.

BMC women's health·2025

Related Experiment Video

Updated: Dec 4, 2025

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids
10:43

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids

Published on: December 23, 2022

3.8K

Primary Esophageal Angiosarcoma.

Lily Gutnik1, Eric Goold2, Jared Madsen3

  • 1Department of Surgery, University of Utah, Salt Lake City, Utah.

The Annals of Thoracic Surgery
|October 23, 2020
PubMed
Summary
This summary is machine-generated.

Primary esophageal angiosarcoma, a rare cancer, presents diagnostic and treatment challenges. This case report highlights unique difficulties in managing this uncommon esophageal malignancy.

More Related Videos

Subculture and Cryopreservation of Esophageal Adenocarcinoma Organoids: Pros and Cons for Single Cell Digestion
10:42

Subculture and Cryopreservation of Esophageal Adenocarcinoma Organoids: Pros and Cons for Single Cell Digestion

Published on: July 6, 2022

4.1K
Establishment and Histological Analysis of Esophageal Organoids Modeling the Progression from Normal to Cancerous Tissues
05:57

Establishment and Histological Analysis of Esophageal Organoids Modeling the Progression from Normal to Cancerous Tissues

Published on: May 30, 2025

785

Related Experiment Videos

Last Updated: Dec 4, 2025

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids
10:43

Modeling Oral-Esophageal Squamous Cell Carcinoma in 3D Organoids

Published on: December 23, 2022

3.8K
Subculture and Cryopreservation of Esophageal Adenocarcinoma Organoids: Pros and Cons for Single Cell Digestion
10:42

Subculture and Cryopreservation of Esophageal Adenocarcinoma Organoids: Pros and Cons for Single Cell Digestion

Published on: July 6, 2022

4.1K
Establishment and Histological Analysis of Esophageal Organoids Modeling the Progression from Normal to Cancerous Tissues
05:57

Establishment and Histological Analysis of Esophageal Organoids Modeling the Progression from Normal to Cancerous Tissues

Published on: May 30, 2025

785

Area of Science:

  • Oncology
  • Pathology
  • Gastroenterology

Background:

  • Primary esophageal angiosarcoma is exceptionally rare, leading to a lack of established diagnostic and treatment protocols.
  • Current management strategies are often adapted from other esophageal cancers and angiosarcoma subtypes.
  • This necessitates a review of diagnostic and therapeutic approaches for this specific condition.

Observation:

  • This case report details a patient with primary esophageal angiosarcoma.
  • The report focuses on the unique challenges encountered during the diagnostic process.
  • It also describes the specific therapeutic hurdles faced in managing this rare cancer.

Findings:

  • The diagnosis of primary esophageal angiosarcoma poses significant challenges due to its rarity.
  • Treatment strategies require careful consideration and adaptation based on limited evidence.
  • The case illustrates the complexities in managing this rare esophageal tumor.

Implications:

  • This case report contributes to the limited body of knowledge on primary esophageal angiosarcoma.
  • It underscores the need for further research into optimal diagnostic methods and treatment regimens.
  • Understanding these challenges can guide future clinical practice for rare esophageal cancers.