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Chitosan-Based Nanocomposites for Glyphosate Detection Using Surface Plasmon Resonance Sensor.
Minh Huy Do1,2, Brigitte Dubreuil1, Jérôme Peydecastaing1
1Laboratoire de Chimie Agro-industrielle, LCA, Université de Toulouse, INRAE, 31030 Toulouse CEDEX 4, France.
Sensors (Basel, Switzerland)
|October 24, 2020
Summary
A novel optical sensor using chitosan (CS) and zinc oxide (ZnO) nanocomposites detects glyphosate with high sensitivity and a low detection limit. This surface plasmon resonance (SPR) method offers a reproducible and selective approach for environmental monitoring.
Area of Science:
- Analytical Chemistry
- Materials Science
- Biotechnology
Background:
- Glyphosate detection is crucial for environmental and food safety.
- Existing methods for glyphosate detection can be complex or lack sensitivity.
- Optical sensing platforms offer potential for rapid and sensitive analyte detection.
Purpose of the Study:
- To develop and optimize a surface plasmon resonance (SPR) based optical sensor for glyphosate detection.
- To investigate the use of chitosan (CS) and its nanocomposites with zinc oxide (ZnO) or graphene oxide (GO) for enhanced sensing performance.
- To characterize the sensor's sensitivity, selectivity, and adsorption mechanisms.
Main Methods:
- Fabrication of chitosan, CS/ZnO, and CS/GO thin films on gold-coated chips via spin coating.
- Characterization of film properties using Fourier-transform infrared spectroscopy (FTIR), atomic force microscopy (AFM), and contact angle measurements.
- Optimization of sensor preparation conditions, including cross-linking and mobile phase parameters (pH, salinity).
Main Results:
- The CS/ZnO thin-film composite demonstrated the highest sensitivity for glyphosate detection, achieving a low limit of detection (LOD) of 8 nM.
- High reproducibility and stability of the sensor were observed.
- Adsorption mechanisms were elucidated using Langmuir models, indicating electrostatic and steric interactions, and formation of outer-sphere surface complexes.
Conclusions:
- The developed SPR sensor based on CS/ZnO nanocomposites is a highly sensitive and reproducible optical method for glyphosate detection.
- The sensor exhibits good selectivity for glyphosate over its metabolite AMPA and other related compounds like glufosinate.
- Further optimization may be needed to mitigate interference from competing molecules in complex aqueous systems.
