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Updated: Aug 19, 2026

Visualization of the Interstitial Cells of Cajal (ICC) Network in Mice
Published on: July 27, 2011
Electron microscopic study on S-100 protein-immunoreactive cells in the guinea pig duodenum, with special reference
1Department of Anatomy, Yamanashi Medical School, Japan.
Abstract:
S-100 protein-immunoreactive cells were studied in the nervous system of the guinea pig duodenum by pre-embedding immunoelectron microscopic cytochemistry. Immunoreactivity of S-100 protein was found diffusely in the cytoplasm of enteroglial cells in the ganglia, nerve strands and autonomic ground plexus. There were fibroblast-like cells containing no S-100 protein immunoreactivity around the ganglia and nerve bundles. Relationship between the fibroblast-like cells and the interstitial cells of Cajal was discussed.
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