Related Experiment Video
Updated: Dec 4, 2025
15:49
Flexible Colonoscopy in Mice to Evaluate the Severity of Colitis and Colorectal Tumors Using a Validated Endoscopic Scoring System
Published on: October 16, 2013
32.3K
The endoluminal pressures during flexible gastrointestinal endoscopy
Yuki Ushimaru1,2, Kiyokazu Nakajima3,4, Masashi Hirota5
1Department of Next Generation Endoscopic Intervention (Project ENGINE), Osaka University Graduate School of Medicine, Center of Medical Innovation and Translational Research, Suite 0912, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan.
Scientific Reports
|October 24, 2020
Summary
This study measured gastrointestinal (GI) endoluminal pressure during esophagogastroduodenoscopy (EGD). Findings establish baseline pressure values, crucial for optimizing visualization during endoscopic procedures.
Area of Science:
- Gastroenterology
- Medical Devices
- Endoscopy
Background:
- Endoscopic insufflation is vital for visualization in flexible gastrointestinal (GI) endoscopy.
- Current manual insufflation methods are subjective and can impact examination quality.
- Objective pressure measurement is needed to standardize endoscopic procedures.
Purpose of the Study:
- To measure the gastrointestinal (GI) endoluminal pressure during flexible GI endoscopy.
- To establish objective pressure benchmarks for improved endoscopic visualization and intervention.
Main Methods:
- Esophagogastroduodenoscopy (EGD) was performed on 80 patients.
- Endoluminal pressure in the esophagus and stomach was measured at 1-second intervals for 1 minute.
- Measurements were taken during observational and diagnostic EGD procedures.
Main Results:
- Average esophageal endoluminal pressure was 8.9 mmHg (range: -3.0 to 20.7 mmHg).
- Average gastric endoluminal pressure was 10.0 mmHg (range: 3.0 to 17.9 mmHg).
- Pressures were not significantly affected by patient factors or endoscopist experience.
Conclusions:
- Successfully obtained GI endoluminal pressure data during EGD.
- These objective pressure measurements can enhance the stability and reproducibility of flexible endoscopic diagnoses and interventions.
- Further data accumulation is recommended for refining endoscopic techniques.
Related Concept Videos
01:26Endoscopic Procedures IV: Sigmoidoscopy and Laproscopy
344
Sigmoidoscopy and laparoscopy are distinct medical procedures that enable physicians to internally inspect different parts of the GI tract. Although they serve different purposes, each is essential for diagnosing and, in some cases, treating various medical conditions.
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
Sigmoidoscopy
Sigmoidoscopy is a diagnostic procedure that uses a flexible sigmoidoscope equipped with a light source and camera to examine the rectum and sigmoid colon. The procedure involves inserting the tube through the anus...
344
01:29Endoscopic Procedures I: Esophagogastroduodenoscopy
595
An Esophagogastroduodenoscopy (EGD) is a diagnostic procedure in which an endoscopist uses a flexible, lighted endoscope to visualize the upper gastrointestinal (GI) tract. The procedure includes visualizing the oropharynx, esophagus, stomach, and the first part of the small intestine, the duodenum.
During an EGD, the endoscope can be used to:
During an EGD, the endoscope can be used to:
595
01:28Endoscopic Procedures III: Video Capsule Endoscopy
498
Capsule endoscopy, or wireless or video capsule endoscopy, is a diagnostic procedure for examining the entire gastrointestinal tract. Patients swallow a capsule about the size of a vitamin tablet. The capsule is equipped with a transmitter, a battery, an LED light source, and a color video camera to capture images throughout the gastrointestinal tract. This procedure is particularly useful for diagnosing conditions such as Crohn's disease, ulcerative colitis, tumors, polyps, ulcers,...
498
01:25Endoscopic Procedures II: Colonoscopy
397
The colon, or large intestine, is the final segment of the digestive system. Its primary functions include absorbing water and vitamins produced by gut bacteria and transforming waste from liquid to solid to form stool. In adults, the large intestine is approximately 5 feet long and consists of four main sections:
397
01:26Endoscopic Procedures V: ERCP
1.8K
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
Patient...
1.8K
01:23Lower GI Series: Barium Enema
875
A Barium Enema, or a lower GI series, is a specialized radiographic examination designed to visualize the lower gastrointestinal tract, specifically the colon and rectum. This procedure is instrumental in diagnosing various conditions such as colorectal cancer, polyps, diverticulosis, and inflammatory bowel disease.
Procedure Details
The examination begins by inserting a lubricated rectal tube into the patient's rectum to administer a radiopaque barium solution. The barium flow is carefully...
Procedure Details
The examination begins by inserting a lubricated rectal tube into the patient's rectum to administer a radiopaque barium solution. The barium flow is carefully...
875