[Diffusion of ceftriaxone in bronchial secretions for 24 hours after a single injection]

The authors have determined the bronchi concentration 1 h, 3 h, 6 h and 24 h after a single muscular injection of ceftriaxone in a series a 13 patient with tracheostomy that received ceftriaxone for prophylaxis. In spite of a large inter-individual variability the result is a good mean ceftriaxone concentration during the first 24 h. Theses results confirms the value or a single daily injection in the treatment of pulmonary injection whose germ is sensitive to the drug.