[Septicemia of urinary origin. Epidemiology and initial antibiotic treatment]

The SES group was formed by the "Ligue Française pour la Prévention des Maladies Infectieuses" to create a diagnostic and therapeutic expert system on septicemia. 461 cases of septicemia were thus collected from january 1 to december 31, 1985. 83 out of these septicemias had an urinary tract portal of entry, 21 were contracted in hospital. The mean age was 65 +/- 21 years (57 +/- 20 years for the 461 cases NS). There were 46 women and 37 men, i.e., a sex-ratio apposite to that of the overall population of septicemias (p less than 0.001). Au urinary lesion was found in 27 patients (p less than 0.001), a neurological disease in 22 (p less than 0.05), a cardiac disease in 24 (NS). 94 bacteria were isolated (11 polymicrobic septicemias) from the blood cultures: 56 E. coli, 7 Klebsiella, 6 Proteus, 7 Gram positive Cocci. 57 out of the 81 patients whose antibiotherapy was known received single-drug treatment (74%, vs 49% for the whole group, p less than 0.001). The evolution was known in 75 patients, uncomplicated in 57 (fatality rate: 11%). Prognosis did not appear to be influenced by the type of pathogen, or the existence of an urinary abnormality.