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Related Concept Videos

Trachea01:22

Trachea

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The trachea, commonly known as the windpipe, is a vital part of the human respiratory system. It serves as a passageway for air to travel between the larynx and the bronchi, allowing oxygen to reach the lungs. Let's explore its anatomical features, dimensions, layers of the tracheal wall, associated muscles, and the functions of its parts.
Anatomical Features:
Location: About half of the trachea is situated in the neck, anterior to the esophagus, and extends from the larynx (at the level of...
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Tracheostomy: Procedure and Tubes01:28

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A tracheostomy is a surgical procedure that creates an artificial opening into the trachea, typically at the second or third cartilaginous ring level. This opening allows the insertion of a tracheostomy tube, which can replace an endotracheal tube, provide mechanical ventilation, bypass an upper airway obstruction, or remove accumulated tracheobronchial secretions.
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Cystic Fibrosis: Management01:24

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Cystic fibrosis (CF) is an autosomal recessive disorder that predominantly affects individuals of Northern European descent, occurring at a rate of 1 in 3500. It is caused by a genetic mutation in a gene on chromosome 7, most commonly the ΔF508 mutation, that codes for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. This results in thicker mucus secretions and obstruction pathologies in multiple organs, including the lungs and sinuses.
Sinus disease and chronic...
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Cystic Fibrosis: Pathogenesis01:23

Cystic Fibrosis: Pathogenesis

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Cystic fibrosis (CF), an autosomal recessive disorder, significantly affects the function of exocrine glands. This genetically inherited disease is characterized by the production of thick and sticky mucus, which can severely affect various organs and systems in the body.
CF is primarily caused by a genetic mutation in a chromosome 7 gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR) protein. The most common gene mutation leading to CF is the ΔF508 mutation,...
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Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques01:30

Cardiopulmonary Resuscitation V: Advanced Airway Management Techniques

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Airway management is essential in emergency and surgical medicine, ensuring ventilation and oxygenation in patients who cannot maintain their own airway. Clinicians use a range of techniques and devices to secure the airway, depending on the patient’s condition and the clinical context. Key methods include endotracheal intubation, rapid sequence intubation (RSI), supraglottic airway devices, and advanced visualization aids. In cases where these approaches fail, surgical airway...
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Related Experiment Video

Updated: Dec 4, 2025

Transuterine Fetal Tracheal Occlusion Model in Mice
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Obstructive fibrinous tracheal pseudomembrane in a cat.

Ran Nivy1,2, Ori Brenner3, Vered Shub2

  • 1Koret School of Veterinary Medicine, The Hebrew University of Jerusalem, Rehovot, Israel.

Journal of Veterinary Internal Medicine
|October 24, 2020
PubMed
Summary

A rare tracheal complication after intubation, obstructive fibrinous tracheal pseudomembrane (OFTP) can cause respiratory distress in cats. Prompt diagnosis and surgical removal of the pseudomembrane lead to full recovery.

Keywords:
distressendotracheal tubeintubationrespiratorytrachea

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Area of Science:

  • Veterinary Medicine
  • Respiratory Physiology

Background:

  • Tracheal intubation (TI) is a common veterinary procedure.
  • While generally safe, TI can rarely lead to serious complications.

Observation:

  • A 1.5-year-old cat exhibited severe respiratory distress 5 weeks post-TI.
  • Radiographs showed significant tracheal narrowing.
  • A 5-cm obstructive tissue was removed from the trachea.

Findings:

  • Microscopic analysis revealed the tissue was an obstructive fibrinous tracheal pseudomembrane (OFTP), containing fibrin, neutrophils, talcum powder, and hair.
  • The cat's condition resolved completely after pseudomembrane removal.

Implications:

  • OFTP, a known complication in humans, should be considered in cats with similar clinical signs and history.
  • Early detection and surgical removal of OFTP are effective treatments for feline respiratory distress post-TI.