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Renal transplantation in children.
C A Sheldon1, G A McLorie, B M Churchill
1Department of Pediatric Surgery, Children's Hospital Medical Center, Cincinnati, Ohio.
Pediatric Clinics of North America
|October 1, 1987
Summary
Pediatric renal transplantation aims for more than kidney function, focusing on growth and development. Individualized therapy plans are crucial for successful outcomes in children with end-stage renal disease (ESRD).
Area of Science:
- Pediatric Nephrology
- Transplantation Medicine
Background:
- Successful renal transplantation in children requires comprehensive management beyond mere renal function replacement.
- Goals include optimizing physical growth, neurodevelopment, and psychosocial adjustment.
Purpose of the Study:
- To highlight the multifaceted goals of pediatric renal transplantation.
- To emphasize the need for individualized therapeutic approaches.
Main Methods:
- Review and application of established principles in pediatric renal transplantation.
- Consideration of various therapeutic modalities for end-stage renal disease (ESRD).
Main Results:
- Increasing success has been achieved in meeting diverse pediatric transplantation goals.
- Effective growth, skeletal, central nervous system, and social development are attainable.
Conclusions:
- Pediatric renal transplantation success hinges on addressing comprehensive developmental needs.
- Judicious pretransplant selection and modified post-transplant protocols are essential for individualized care.