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Activity of Antioxidant Enzymes in the Regional Blood Flow during Pelvic Venous Disorders in Women
M A Darenskaya1, A A Semendyaev2,3, D A Stupin2,3
1Research Centre for Family Health and Human Reproduction Problems, Irkutsk, Russia. marina_darenskaya@inbox.ru.
Abstract:
Activity of some antioxidant enzymes (superoxide dismutase, catalase, and glutathionedependent enzymes), as well as the level of LPO products in the region regional blood flow (collateral branches of the main trunks of ovarian veins) in women with pelvic venous disorders were studied. A compensatory increase in activity of superoxide dismutase, catalase, and glutathione peroxidase during stage I of the disease was found; during stage II, superoxide dismutase activity decreased and glutathione peroxidase increased, while during stage III, pronounced decrease in activities of all studied enzymes was observed. The level of lipid peroxidation products in the regional blood flow increased as the disease progressed, with maximum values in the third stage.
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