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Related Concept Videos

Pharmacovigilance01:19

Pharmacovigilance

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Post-marketing surveillance is a critical component of pharmaceutical regulation, often uncovering unanticipated adverse drug reactions (ADRs) once a drug is widely used over an extended period.
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In some cases, there...
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Analysis of Population Pharmacokinetic Data01:12

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Analysis of population pharmacokinetic data involves studying the behavior of drugs within diverse populations to understand their pharmacokinetic parameters. Traditional pharmacokinetic methods typically involve collecting samples from a few individuals and estimating these parameters. While these methods are commonly used, they have limitations in capturing the variability in drug response among individuals or heterogeneous populations. Population pharmacokinetics is employed to address these...
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Dosage Regimens: Partial Pharmacokinetic Parameters01:01

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It is not uncommon for complete drug pharmacokinetic profiles to remain elusive in pharmacokinetics. This necessitates certain educated assumptions by pharmacokineticists to determine appropriate dosage regimens without comprehensive pharmacokinetic data from animal or human studies. One prevalent assumption is setting the bioavailability factor, denoted as F, to 1 or 100%. This assumption caters to the scenario where a drug doesn't achieve full systemic absorption, resulting in the patient...
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Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

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As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
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Factors Influencing Drug Absorption: Pharmaceutical Parameters01:28

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Solid dosage forms such as tablets and capsules undergo rigorous manufacturing processes to ensure stability and effectiveness. Their dissolution and absorption properties are influenced significantly by the choice of excipients (inactive ingredients that serve various roles in the formulation), and the methodology applied during production. The manufacturing parameters, such as compression force and granulation techniques, significantly affect dissolution rates. Elevated compression forces...
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Drug regulation encompasses the management of drug usage by evaluating its safety and efficacy through assessments conducted by regulatory authorities. Regrettably, the history of drug regulation is marred by several catastrophic events. One such incident is the Elixir Sulfanilamide tragedy, in which the toxic compound diethyl glycol was included in a sweet-tasting medication, leading to numerous fatalities. This event prompted the enactment of the Food, Drug, and Cosmetic Act in 1938. Under...
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[Moroccan pharmacy students' knowledge and perceptions about pharmacovigilance].

N Nchinech1, Z Lachhab2, M Obtel1

  • 1Faculté de médecine et de pharmacie, université Mohammed-V de Rabat, Rabat, Morocco.

Annales Pharmaceutiques Francaises
|October 25, 2020
PubMed
Summary

Educational work groups significantly improved pharmacovigilance (PV) knowledge among pharmacy students. Post-intervention, students demonstrated better understanding and preparedness for adverse drug reaction (ADR) reporting.

Keywords:
ConnaissanceFormation en pharmacovigilanceKnowledgePerceptionPharmacovigilance trainingPharmacy studentsÉtudiants pharmaciens

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Area of Science:

  • Pharmacovigilance and pharmaceutical education.

Background:

  • Pharmacovigilance (PV) is crucial for drug safety.
  • Assessing student knowledge and perception is key to improving pharmaceutical education.

Purpose of the Study:

  • To evaluate the impact of educational work groups on pharmacovigilance knowledge and perception.
  • To assess the preparedness of 2nd-year pharmacy students for adverse drug reaction (ADR) reporting.

Main Methods:

  • A descriptive study using pre- and post-intervention questionnaires.
  • Targeted 2nd-year pharmacy students at a Moroccan faculty of medicine and pharmacy.
  • Educational work groups were implemented to enhance understanding of PV and ADR reporting.

Main Results:

  • High participation rates (88.5% pre, 95.9% post) were achieved.
  • Pre-intervention, only 27.7% knew the ADR reporting sheet, and 75.92% felt unprepared to report ADRs.
  • Post-intervention, preparedness significantly improved, with only 25.92% reporting inability to report ADRs. Perception remained favorable.

Conclusions:

  • Educational work groups effectively improved pharmacovigilance knowledge and reporting preparedness.
  • Students expressed a desire for more PV education.
  • The study led to the implementation of PV working groups for higher-level pharmacy students.