Mammary Paget's disease diagnosed with reflectance confocal microscopy

Mammary Paget's disease (MPD) is a rare breast carcinoma represented with an eczematoid cutaneous manifestation. Imitating inflammatory or infectious diseases, it makes early diagnosis and prompt treatment difficult. Non-invasive imaging examinations such as reflectance confocal microscopy (RCM) could extend assistance in making a diagnosis because of its near-cellular resolution in skin diseases. Herein, the RCM feature of two cases of MPD, and the corresponding dermoscopy, ultrasonography examination and immunohistochemistry staining results were described.