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Updated: Dec 4, 2025

Ultrasound-guided Botulinum Toxin-A Injections: A Method of Treating Sialorrhea
Published on: November 9, 2016
Transient localized cutaneous reaction after onabotulinumtoxinA aesthetic injection
Emily K Haque1, Yousef R Darwish1, Claire S Reddick2
1College of Medicine, Texas A&M Health Science Center, Dallas, Texas.
Abstract:
OnabotulinumtoxinA (ONA) is an injectable neurotoxin frequently used to temporarily halt the skin changes associated with aging. Side effects are rare and usually minor, such as bruising, injection site discomfort, and headaches. However, a true hypersensitivity reaction is a serious adverse effect, and clinicians should not attempt another trial if allergy is suspected. We present a case of a benign localized cutaneous reaction following ONA injections in the forehead without signs of an allergic reaction. The rash resolved with topical hydrocortisone, and the patient was able to undergo another trial of injections without recurrence.
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