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COVID-19-Associated Coagulopathy: A Case Report of Thrombosis despite Therapeutic Anticoagulation
Habiba Hussain1, Matthew Sehring2, Bhagat Singh Aulakh2
1Department of Internal Medicine, University of Illinois College of Medicine at Peoria, Peoria, IL, USA.
Abstract:
The Coronavirus disease (COVID-19) pandemic, caused by Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has led to tremendous morbidity and mortality. Various inflammatory markers have been monitored and considered to be associated with disease prognosis. One of the major sources of comorbidity involved has been development of thrombosis alongside the infection. This prothrombotic phenomenon considered, COVID-19-associated coagulopathy (CAC), has been the center of discussion in dealing with this infection. There still remains ambiguity regarding management guidelines for thromboprophylaxis dosing and therapeutic anticoagulation. We present a case of severe SARS-CoV-2 infection complicated by thrombosis despite therapeutic anticoagulation contributing to prolonged intensive care unit and hospital stay.
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