Related Experiment Video

Updated: Dec 4, 2025

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis
08:46

A Neonatal Imaging Model of Gram-Negative Bacterial Sepsis

Published on: August 12, 2020

6.7K

Severe necrotizing pneumonia complicated by empyema in a neonate

Henry Zapata1, Andrew Wahba1

  • 1Department of Pediatrics, McGovern Medical School at the University of Texas Health Science Center, Houston, TX, USA.

Respiratory Medicine Case Reports
|October 26, 2020
PubMed

Insights

Necrotizing pneumonia and empyema are severe conditions. This case study highlights a successful non-surgical treatment for a neonate with severe necrotizing pneumonia and empyema caused by MRSA.

Area of Science:

  • Neonatal Medicine
  • Infectious Diseases
  • Pulmonology

Background:

  • Necrotizing pneumonia is a severe lung infection with tissue destruction and abscess formation.
  • Empyema, a complication of pneumonia, is rare in neonates, with limited reported cases.
  • Methicillin-resistant Staphylococcus aureus (MRSA) is a significant pathogen in healthcare-associated infections.

Observation:

  • A healthy term neonate presented with late-onset sepsis.
  • The sepsis was attributed to severe necrotizing pneumonia with multifocal lung abscesses.
  • Advanced stage empyema was diagnosed concurrently with the pneumonia.

Findings:

  • The neonate had bacteremia caused by MRSA.
  • The patient exhibited severe necrotizing pneumonia and stage 2 empyema.
  • Successful treatment was achieved without surgical intervention.

Implications:

  • This case represents the youngest reported patient with multifocal lung abscesses and stage 2 empyema.
  • Non-surgical management can be effective for severe necrotizing pneumonia and empyema in neonates.
  • Highlights the importance of considering MRSA in neonatal sepsis with severe pulmonary complications.
Keywords:
EmpyemaMethicillin resistant staphylococcus aureusNecrotizing pneumonia

More Related Videos

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus06:15

Protocol and Guidelines for Point-of-Care Lung Ultrasound in Diagnosing Neonatal Pulmonary Diseases Based on International Expert Consensus

Published on: March 6, 2019

51.4K
Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs08:58

Development of a Neonatal Piglet Acute Lung Injury Model Recreating the Early Environment of Preterm Infant Lungs

Published on: October 31, 2025

374

Related Concept Videos

Pneumonia III: Complications and Assessment01:30

Pneumonia III: Complications and Assessment

Pneumonia poses the potential for numerous complications that warrant consideration. These complications include the following:
662
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
568
Pneumonia II: Pathophysiology01:29

Pneumonia II: Pathophysiology

The pathophysiology of pneumonia involves the following steps:
2.1K
Pneumonia IV: Management01:28

Pneumonia IV: Management

The treatment of pneumonia varies based on its severity and the causative pathogen. Here is a structured approach to managing pneumonia, integrating pharmaceutical and supportive care strategies.
Bacterial Pneumonia Treatment
For bacterial pneumonia, antibiotics serve as the cornerstone of therapy. Initial treatment often begins with empirical antibiotics, tailored to the anticipated causative organism and adjusted based on culture results. Key antibiotic choices include:
624
Pneumonia V: Nursing management and Prevention01:30

Pneumonia V: Nursing management and Prevention

Nursing management of pneumonia involves promoting airway patency, facilitating rest and conserving energy, encouraging fluid intake, maintaining nutrition, and educating patients.
The nurse must practice strict medical asepsis and adhere to infection control guidelines to minimize healthcare-associated infections.
Enhance airway patency
Position the patient correctly to facilitate drainage of the affected lung segments. Manual or mechanical percussion and vibration can also be employed....
3.1K
Acute Pyelonephritis II: Diagnostic Studies and Management01:28

Acute Pyelonephritis II: Diagnostic Studies and Management

Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
172