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Is the shielding effect of cholecalciferol in SARS CoV-2 infection dependable? An evidence based unraveling

Shaik Lahoor Basha1, Sake Suresh2, V V Ashok Reddy3

  • 1Department of Medical Affairs, HealthMinds, Bengaluru, Karnataka, 560038, India.

Clinical Epidemiology and Global Health
|October 26, 2020
PubMed

Insights

Maintaining normal vitamin D3 levels may reduce COVID-19 severity and mortality risk. Further randomized clinical trials are needed to confirm vitamin D

Area of Science:

  • Immunology
  • Infectious Diseases
  • Nutritional Science

Background:

  • Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was declared a global health emergency by the WHO.
  • Specific treatments for SARS-CoV-2 are still under development.
  • Vitamins are being investigated for their role in managing COVID-19.

Purpose of the Study:

  • To review the available evidence on the role of vitamin D in COVID-19.
  • To highlight the need for further research into vitamin D's impact on COVID-19 outcomes.

Main Methods:

  • Literature review of existing studies on vitamin D and COVID-19.
  • Analysis of epidemiological data related to vitamin D levels and COVID-19 outcomes.

Main Results:

  • Preliminary evidence suggests a potential link between normal vitamin D3 levels and reduced COVID-19 severity.
  • Maintaining adequate vitamin D levels may be associated with a lower risk of mortality.

Conclusions:

  • There is an urgent need for randomized clinical trials to establish the definitive role of vitamin D in COVID-19 prognosis.
  • Further research should explore the impact of vitamin D on epidemiological outcomes across different latitudes.
Keywords:
CathelicidinDiabetesHypertensionInfluenzaLatitudePneumonia

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