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An extract from amazonian fruit, camu-camu (<i>Myrciaria dubia</i>), attenuates DSS-induced gut-liver axis alterations by improving intestinal morphology and barrier-related gene expression and reducing hepatic histological damage and oxidative stress <i>in ovo</i> (<i>Gallus gallus</i>).

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Dietary Plant-Origin Bio-Active Compounds, Intestinal Functionality, and Microbiome.

Elad Tako1

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Plant-origin bioactive compounds in food significantly impact gut health and nutrient absorption. Research highlights their role in enhancing intestinal function and the microbiome for overall human development.

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Area of Science:

  • Nutritional Science
  • Microbiology
  • Human Health

Background:

  • Plant-origin bioactive compounds are increasingly recognized for their health benefits.
  • Their effects on human health are complex, involving host and gut microbiome interactions.
  • Recent research focuses on their role in intestinal functionality and nutrient bioavailability.

Discussion:

  • Plant bioactives influence duodenal brush border membrane, morphology, and beneficial bacteria.
  • Evidence suggests a crucial role in mineral and nutrient absorption.
  • The gut microbiome metabolizes food constituents, contributing to health outcomes.

Key Insights:

  • Plant-origin compounds modulate gut microbiome composition and diversity.
  • They enhance the function of brush border enzymes and transporters.
  • These compounds are vital for nutrient bioavailability and human development.

Outlook:

  • Further research is needed to elucidate specific mechanisms of action.
  • Understanding these interactions can inform public health recommendations.
  • Dietary strategies incorporating plant bioactives may optimize gut health.