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Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro
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Human Liver Microphysiological System for Assessing Drug-Induced Liver Toxicity In Vitro

Published on: January 31, 2022

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[Liver failure and glucocorticoid resistance]

X Wang1, H R Xu2, Y D Wang3

  • 1Department of Infectious Diseases, Third Hospital of Hebei Medical University, Shijiazhuang 050051, China; Baodi District Hospital of Traditional Chinese Medicine in Tianjin, Tianjin 301800, China.

Zhonghua Gan Zang Bing Za Zhi = Zhonghua Ganzangbing Zazhi = Chinese Journal of Hepatology
|October 27, 2020
PubMed
Summary

Glucocorticoid resistance in liver failure patients is likely due to P-glycoprotein activity and signaling pathway issues. Understanding these mechanisms is key for effective treatment timing and improving patient outcomes.

Keywords:
GlucocorticoidsInflammatory reactionLiver failureSignal pathway

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