![Quantification of Atherosclerotic Plaque Activity and Vascular Inflammation using [18-F] Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography FDG-PET/CT](/_next/image?url=https%3A%2F%2Fcloudfront.jove.com%2FCDNSource%2Fteasers%2F3777.jpg&w=3840&q=50)
Large vessel vasculitis: imaging standards of 18F-FDG PET/CT
Ukihide Tateishi1, Junichi Tsuchiya2, Kota Yokoyama2
1Department of Diagnostic Radiology, Tokyo Medical and Dental University, 1-5-45, Yushima, Bunkyo-ku, Tokyo, Japan. ttisdrnm@tmd.ac.jp.
Japanese Journal of Radiology
|October 27, 2020
Summary
Positron emission tomography (PET) improves large-vessel vasculitis (LVV) diagnosis. 18F-FDG PET/CT imaging standards are presented for earlier detection and monitoring of LVV subtypes like Takayasu arteritis and giant cell arteritis.
Area of Science:
- Nuclear medicine
- Radiology
- Immunology
Background:
- Large-vessel vasculitis (LVV) diagnosis and monitoring pose challenges.
- Corticosteroids and immunosuppression are primary treatments but may be insufficient.
- Laboratory tests alone often fail to track disease activity.
Purpose of the Study:
- To review current concepts and imaging standards for 18F-FDG PET/CT in LVV.
- To highlight the role of PET in improving diagnostic accuracy for LVV.
- To explore glucose metabolism as a potential biomarker source.
Main Methods:
- Systematic review and meta-analysis of existing literature.
- Focus on 18F-FDG PET/CT imaging techniques and interpretation.
- Discussion of current standards for PET/CT in suspected LVV cases.
Main Results:
- 18F-FDG PET technology has significantly enhanced diagnostic accuracy in LVV.
- Earlier diagnosis of LVV is achievable with 18F-FDG PET.
- PET may offer insights into disease activity where lab tests fall short.
Conclusions:
- 18F-FDG PET/CT is a valuable tool for diagnosing and potentially monitoring LVV.
- Standardized imaging protocols are crucial for optimal use of PET/CT in LVV.
- Further research into glucose metabolism biomarkers is warranted.
More Related Videos
Related Concept Videos
01:13Radiological Investigation III: Pulmonary Angiogram and PET Scan
287
Radiological investigations are paramount in the diagnosis and management of various pulmonary diseases. Two essential investigations are the Pulmonary Angiogram and the Positron Emission Tomography (PET) Scan.
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...
287
01:19Imaging Studies VII: Vascular Imaging
158
DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
158
01:28Imaging Studies for Cardiovascular System V: CT
161
Cardiac computed tomography (CT) scanning is an advanced cardiac imaging technique that utilizes CT technology, with or without intravenous (IV) contrast, to produce accurate cross-sectional virtual slices of specific areas of the heart, coronary circulation, and major blood vessels such as the aorta, pulmonary veins, and arteries. The computer processes these slices to generate three-dimensional images. Multidetector CT (MDCT) is a rapid form of CT scanning that captures multiple slices...
161
01:25Imaging Studies II: Positron Emission Tomography and Scintigraphy
349
Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
Fundamental Principles of PET
349