Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

When does sucrose increase appetite and adiposity?

I Ramirez1

  • 1Monell Chemical Senses Center, Philadelphia, PA 19104.

Appetite
|August 1, 1987
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Population-based survey on menopausal symptoms and treatment use.

Climacteric : the journal of the International Menopause Society·2022
Same author

Fatal Disseminated Infection by Trichosporon asahii Under Voriconazole Therapy in a Patient with Acute Myeloid Leukemia: A Review of Breakthrough Infections by Trichosporon spp.

Mycopathologia·2019
Same author

Computer vision-based diameter maps to study fluoroscopic recordings of small intestinal motility from conscious experimental animals.

Neurogastroenterology and motility·2017
Same author

Protothecal bursitis after simultaneous kidney/liver transplantation: a case report and review.

Transplant infectious disease : an official journal of the Transplantation Society·2016
Same author

Histoplasmosis in renal transplant patients in an endemic area at a reference hospital in Medellin, Colombia.

Transplantation proceedings·2014
Same author

Epidermal growth factor protects the heart against low-flow ischemia-induced injury.

Journal of physiology and biochemistry·2010
Same journal

Multivariate Patterns of Food Image Evaluations Distinguish Obesity: A Key Role of Highly Processed Foods.

Appetite·2026
Same journal

It is not what it seems to be. Analysing non-vegetarian consumers' implicit and explicit responses towards a traditional plant-based dry-cured fermented sausage.

Appetite·2026
Same journal

The mediating role of eating behaviors in the association between adverse childhood experiences and central obesity among young adults.

Appetite·2026
Same journal

Gratitude for food as a driver of improved dietary behaviors: A scoping review.

Appetite·2026
Same journal

Food noise: Conceptual, methodological, and ethical considerations.

Appetite·2026
Same journal

Capabilities, Opportunities, and Motivations Influencing Young People's Sustainable and Healthy Food-Related Behaviours: A Systematic Review.

Appetite·2026
See all related articles

Rodent studies on sucrose feeding reveal that the method of administration significantly impacts results. Animal models do not conclusively support the notion that dietary sucrose causes obesity in humans.

Area of Science:

  • Nutrition Science
  • Animal Models
  • Metabolic Research

Background:

  • Sucrose consumption is debated as a cause of obesity.
  • Rodent studies utilize two primary sucrose feeding methods: nutritional and solution.
  • These methods yield divergent results, complicating interpretations.

Purpose of the Study:

  • To compare the effects of two sucrose feeding methods in rodents.
  • To analyze how feeding method influences metabolic outcomes and weight gain.
  • To evaluate the relevance of rodent sucrose studies to human obesity.

Main Methods:

  • Nutritional method: Replacing dietary starch with sucrose.
  • Solution method: Providing sucrose solutions to animals on a complete diet.
  • Comparison of weight gain, adiposity, and dietary interactions between methods.

Related Experiment Videos

Main Results:

  • Solution method is more effective for inducing obesity in most rodents.
  • Feeding methods influence interactions with dietary fat/protein and meal patterns.
  • Sucrose's effect may involve fat oxidation (nutritional) or caloric density (solution).

Conclusions:

  • Methodological differences in rodent sucrose feeding studies are critical.
  • Observed discrepancies challenge the direct causal link between sucrose and human obesity.
  • Animal studies, due to feeding variations, do not support sucrose as a primary driver of human obesity.