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Related Experiment Video

Updated: Jul 2, 2026

Image-guided, Laser-based Fabrication of Vascular-derived Microfluidic Networks

Image-guided, Laser-based Fabrication of Vascular-derived Microfluidic Networks

Published on: January 3, 2017

A rapid, nondestructive method for vascular network visualization.

Austin Veith¹, Aaron B Baker¹

¹University of Texas at Austin, Austin, TX, USA.

|October 28, 2020

Summary

This summary is machine-generated.

We developed a new, non-damaging method for imaging blood vessels in tissues using iodine-enhanced micro-CT and deep learning. This technique allows for detailed 3D reconstruction of vascular networks for further analysis.

Keywords:

blood vessels convolutional neural networks imaging microCT microvasculature nondestructive vasculature visualization

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An In Vitro 3D Model and Computational Pipeline to Quantify the Vasculogenic Potential of iPSC-Derived Endothelial Progenitors

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An In Vitro 3D Model and Computational Pipeline to Quantify the Vasculogenic Potential of iPSC-Derived Endothelial Progenitors

An In Vitro 3D Model and Computational Pipeline to Quantify the Vasculogenic Potential of iPSC-Derived Endothelial Progenitors

Published on: May 13, 2019

Area of Science:

Biomedical Engineering
Medical Imaging
Pathology

Background:

Quantitative analysis of blood vessel networks is crucial for studying diseases in animal models.
Existing methods may not allow for subsequent analyses on the same tissue sample.

Purpose of the Study:

To present a nondestructive technique for in situ blood vessel imaging in harvested tissues.
To enable subsequent histological and other analyses on the same tissue sample.
To augment existing analysis methods with 3D vascular reconstruction.

Main Methods:

Iodine-enhanced micro-computed tomography (micro-CT) for tissue contrast.
Deep learning algorithm for automated vasculature segmentation.
Integration of imaging with downstream tissue analysis.

Main Results:

Successful visualization of intact vasculature in harvested tissues.
Demonstration of the method's compatibility with subsequent histological analysis.
Generation of detailed three-dimensional reconstructions of vascular networks.

Conclusions:

The described technique offers a simple yet powerful approach for nondestructive blood vessel imaging.
It provides valuable insights into complex vascular changes in disease models.
The method facilitates comprehensive analysis by combining imaging with histology.