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Eosinophilic peritonitis with colon cancer: a case report
Ryo Ataka1,2, Hirokazu Tanaka3,4, Shintaro Yagi2
1Department of General Surgery, Tango Central Hospital, 158-1 Sugitani, Mineyama-Cho, Tango, Kyoto, 627-8555, Japan.
BMC Gastroenterology
|October 28, 2020
Summary
Eosinophilic peritonitis, a rare condition, was linked to colon cancer in a patient presenting with massive ascites. Steroid treatment resolved the ascites, and subsequent surgery confirmed the cancer diagnosis.
Area of Science:
- Gastroenterology
- Oncology
- Pathology
Background:
- Eosinophilic gastrointestinal disorders (EGIDs) are rare inflammatory conditions affecting any part of the GI tract.
- Malignant or benign tumors associated with EGIDs are exceptionally uncommon.
Observation:
- A 62-year-old male presented with abdominal fullness and massive ascites.
- Ascitic fluid analysis revealed a high eosinophil count without malignancy.
- Endoscopy identified colon cancer, and biopsies showed significantly higher eosinophil counts in cancer lesions.
Findings:
- Exploratory laparoscopy revealed cloudy ascites and mesenteric thickening with a high eosinophil infiltration.
- Pathological examination of the mesentery confirmed abundant eosinophils, excluding malignancy.
- These findings suggested a correlation between eosinophilic peritonitis and colon cancer.
Implications:
- This case highlights eosinophilic peritonitis as a potential paraneoplastic manifestation of colon cancer.
- Laparoscopy is valuable for diagnosing the cause of ascites in such cases.
- Histopathological analysis is crucial for understanding the association between eosinophilia and gastrointestinal malignancies.
