Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Predicting positive <i>Clostridioides difficile</i> test results using large-scale longitudinal data of demographics and medication history.

Heliyon·2025

Same author

Letter to the editor.

American journal of infection control·2023

Same author

A Smartphone-Based Tool for Rapid, Portable, and Automated Wide-Field Retinal Imaging.

Translational vision science & technology·2018

Same author

Emphysematous pyelonephritis: the impact of urolithiasis on disease severity.

Translational andrology and urology·2016

Same author

Standardized Infection Ratio for Surgical Site Infection after Colon Surgery: Discord in Models Measuring Healthcare Quality.

Infection control and hospital epidemiology·2016

Same author

Sterilization and High-Level Disinfection Update.

AORN journal·2015

Search research articles

Related Experiment Video

Updated: Dec 3, 2025

Reconstruct Human Retinoblastoma In Vitro

Reconstruct Human Retinoblastoma In Vitro

Published on: October 11, 2022

Case Report: Adult Retinoblastoma Progression in 19 Months.

Liang Zhou¹, Xiao-Hua Zhu¹, Ke Zhang²

¹Department of Ophthalmology, the Second Xiangya Hospital, Central South University, Changsha, Hunan, China.

Optometry and Vision Science : Official Publication of the American Academy of Optometry

|October 28, 2020

Summary

Adult onset retinoblastoma is exceptionally rare, often misdiagnosed due to atypical presentations. This case highlights the importance of considering this rare intraocular malignancy in adults, even with delayed presentation.

More Related Videos

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice

Published on: August 4, 2011

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report

Published on: February 12, 2018

Related Experiment Videos

Last Updated: Dec 3, 2025

Reconstruct Human Retinoblastoma In Vitro

Reconstruct Human Retinoblastoma In Vitro

Published on: October 11, 2022

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice

Establishment and Propagation of Human Retinoblastoma Tumors in Immune Deficient Mice

Published on: August 4, 2011

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report

Regenerative Therapy by Suprachoroidal Cell Autograft in Dry Age-related Macular Degeneration: Preliminary In Vivo Report

Published on: February 12, 2018

Area of Science:

Ophthalmology
Pediatric Oncology
Medical Diagnostics

Background:

Retinoblastoma is the most common pediatric intraocular cancer.
Adult onset retinoblastoma is exceedingly rare, with atypical presentations often leading to misdiagnosis.
Early detection and accurate diagnosis are crucial for managing intraocular malignancies.

Observation:

A 34-year-old woman presented with a 19-month history of an intraocular mass.
Clinical examination revealed a whitish-pink retinal mass with vascular leakage on angiography.
Ultrasound confirmed an enlarging intraocular mass without calcification.

Findings:

The patient underwent enucleation due to the tumor's atypical features and delayed presentation.
Histopathology confirmed the diagnosis of retinoblastoma in the enucleated eye.
The tumor exhibited rapid growth and malignant features necessitating prompt intervention.

Implications:

Adult onset retinoblastoma requires differentiation from other retinal tumors like primitive neuroectodermal tumors.
Eye care practitioners must maintain awareness of adult retinoblastoma possibilities.
While tumors can grow rapidly, needle biopsy is not recommended for diagnosis.