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Updated: Dec 3, 2025

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Meta-Analysis of Risk Association between Interleukin-17A Gene Polymorphism and Chronic Periodontitis
P K Sasikumar1, Sheeja S Varghese2, Thanga Kumaran3
1Department of Periodontics, JKKN Dental College, Namakkal, Tamil Nadu, India.
Abstract:
The association of genetic polymorphisms with periodontitis has been studied extensively. The interleukin-7 (IL-17) is a group of cytokines, which comprises six different molecules (IL-17A, B, C, D, E, and F). Among this, IL-17A is the most commonly understood cytokine, and its polymorphism plays a critical role in inflammatory diseases and periodontal inflammation. The present study was aimed at pooling the data available for meta-analysis and to evaluate whether IL-17A (rs2275913) polymorphism is associated with the susceptibility of chronic periodontitis.

