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Ozone Therapy in Periodontics: A Meta-analysis
R Deepthi1, Shivaprasad Bilichodmath1
1Department of Periodontology, Rajarajeswari Dental College and Hospital, Bengaluru, Karnataka, India.
Contemporary Clinical Dentistry
|October 28, 2020
Summary
Ozone therapy, known for antimicrobial and regenerative properties, effectively complements mechanical treatments for periodontitis. This adjunctive approach shows promise in managing gingival and periodontal diseases at all stages.
Area of Science:
- Dentistry
- Periodontology
- Ozone Therapy
Background:
- Gingival and periodontal diseases are significant dental concerns.
- Ozone possesses known antimicrobial and tissue regenerative properties.
- Ozone is indicated for various stages of gingival and periodontal diseases.
Purpose of the Study:
- To review the literature on ozone therapy as an adjunct to mechanical therapy for periodontitis.
- To evaluate the efficacy of ozone in conjunction with standard periodontitis treatments.
Main Methods:
- A comprehensive literature search was conducted from January 1, 2010, to July 30, 2018.
- Databases searched included PubMed, Medline, Embase, Cochrane, and Google Scholar, along with hand searching.
- Six studies were included in the meta-analysis after initial screening of 123 articles.
Main Results:
- A high degree of heterogeneity was observed among the selected studies (Q-value = 10.241, I² = 80.49%).
- Funnel plots indicated an absence of publication bias.
- Ozone therapy demonstrated effectiveness as an adjunct to scaling and root planing.
Conclusions:
- Ozone therapy is an effective adjunct to conventional mechanical therapy for periodontitis.
- The findings support the use of ozone in managing periodontal conditions.
- Further research may be warranted to address study heterogeneity.

