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Acute zonal occult outer retinopathy presenting as optic neuritis
Pai-Huei Peng1, Tong-Sheng Lee1, Cheng-Kuo Cheng1,2,3
1Department of Ophthalmology, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
Taiwan Journal of Ophthalmology
|October 28, 2020
Summary
Acute zonal occult outer retinopathy (AZOOR) can mimic optic neuritis, presenting diagnostic challenges. Early differentiation is crucial for accurate ophthalmologic diagnosis and timely treatment.
Area of Science:
- Ophthalmology
- Neuro-ophthalmology
Background:
- Acute zonal occult outer retinopathy (AZOOR) is an outer retinal disorder causing sudden visual function loss.
- Distinguishing AZOOR from optic neuritis is clinically significant due to overlapping symptoms.
Observation:
- A case of AZOOR presented with symptoms mimicking optic neuritis in a 17-year-old male.
- Clinical findings included subtle disc hyperemia, hyperpigmentation, enlarged blind spot, and autofluorescence changes.
Findings:
- Optical coherence tomography showed ellipsoid line loss, consistent with AZOOR.
- Visual-evoked potential and MRI findings suggested optic neuritis, highlighting diagnostic ambiguity.
Implications:
- Ophthalmologists must carefully differentiate AZOOR from optic neuritis based on a comprehensive evaluation.
- Accurate diagnosis is essential for appropriate patient management and preventing misdiagnosis.
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