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Separation of Immune Cell Subpopulations in Peripheral Blood Samples from Children with Infectious Mononucleosis
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Elevated monocytic myeloid-derived suppressor cells positively correlate with infection frequency in children with
Jianjian Ji1, Lishun Ren1, Yuling Liu2
1Jiangsu Key Laboratory of Pediatric Respiratory Disease, Institute of Pediatrics, Nanjing University of Chinese Medicine, Nanjing, China.
European Journal of Immunology
|October 28, 2020
Abstract:
In children with recurrent respiratory tract infections (RRTIs), the percentages and numbers of monocytic myeloid-derived suppressor cells (MDSCs) were elevated. The elevated MDSCs positively correlate with respiratory tract infection frequency in RRTIs children. The elevated MDSCs can inhibit CD8+ T-cells proliferation in RRTIs children.
Keywords:
CD8+ T cellinfection frequencymyeloid-derived suppressor cellsrecurrent respiratory tract infections
