Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Targeted Cancer Therapies02:57

Targeted Cancer Therapies

8.2K
The targeted cancer therapies, also known as “molecular targeted therapies,” take advantage of the molecular and genetic differences between the cancer cells and the normal cells. It needs a thorough understanding of the cancer cells to develop drugs that can target specific molecular aspects that drive the growth, progression, and spread of cancer cells without affecting the growth and survival of other normal cells in the body.
There are several types of targeted therapies against...
8.2K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A senescent metabolism-modulating hierarchical scaffold restores NAD<sup>+</sup> homeostasis and redox balance for aged bone repair.

Bioactive materials·2026
Same author

Inorganic biomaterials-reinforced printable hydrogel modulating regenerative microenvironments for tissue repair.

Biofabrication·2026
Same author

Bioactive Magnesium Silicate Activating Myocardial Energy Metabolism For Infarcted Myocardium Repair.

Exploration (Beijing, China)·2026
Same author

Genome-Wide Characterization of Citrus NBS-LRR Genes and Integrative Analysis of a Candidate Gene Associated with Alternaria Brown Spot-Related QTL.

Plants (Basel, Switzerland)·2026
Same author

Bi-Polar Bioenergetic Intervention via a Pathology Self-Adaptive Single-Atom Nanocatalyst for Diabetic Tumor Postoperative Management.

Nano-micro letters·2026
Same author

New features of Peristediidae fishes in the South China Sea.

Journal of fish biology·2026

Related Experiment Video

Updated: Dec 3, 2025

Microfluidics-based High-throughput Circulating Tumor Cell Sorting and Single-cell Sequencing Technology
09:45

Microfluidics-based High-throughput Circulating Tumor Cell Sorting and Single-cell Sequencing Technology

Published on: November 14, 2025

179

Nanoplatform-based cascade engineering for cancer therapy.

Jiajie Chen1, Yufang Zhu, Chengtie Wu

  • 1State Key Laboratory of High Performance Ceramics and Superfine Microstructure, Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai, 200050, P. R. China. zjf2412@163.com jlshi@mail.sic.ac.cn.

Chemical Society Reviews
|October 28, 2020
PubMed
Summary
This summary is machine-generated.

Nanotechnology-based cascade engineering optimizes cancer therapies by designing smart nanoplatforms. This approach enhances anti-tumor efficacy and reduces side effects for personalized cancer treatment.

More Related Videos

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
14:20

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Published on: June 13, 2014

16.9K
A Multiplexed Luciferase-based Screening Platform for Interrogating Cancer-associated Signal Transduction in Cultured Cells
10:13

A Multiplexed Luciferase-based Screening Platform for Interrogating Cancer-associated Signal Transduction in Cultured Cells

Published on: July 3, 2013

11.5K

Related Experiment Videos

Last Updated: Dec 3, 2025

Microfluidics-based High-throughput Circulating Tumor Cell Sorting and Single-cell Sequencing Technology
09:45

Microfluidics-based High-throughput Circulating Tumor Cell Sorting and Single-cell Sequencing Technology

Published on: November 14, 2025

179
Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?
14:20

Polymalic Acid-based Nano Biopolymers for Targeting of Multiple Tumor Markers: An Opportunity for Personalized Medicine?

Published on: June 13, 2014

16.9K
A Multiplexed Luciferase-based Screening Platform for Interrogating Cancer-associated Signal Transduction in Cultured Cells
10:13

A Multiplexed Luciferase-based Screening Platform for Interrogating Cancer-associated Signal Transduction in Cultured Cells

Published on: July 3, 2013

11.5K

Area of Science:

  • Biomedical Engineering
  • Nanotechnology
  • Oncology

Background:

  • Conventional cancer therapies face challenges due to limitations and biological complexities.
  • Nanotechnology offers advanced solutions for precise and effective cancer treatment.

Purpose of the Study:

  • To review recent advances in nanoplatform-based cascade engineering for cancer therapy.
  • To discuss the design of smart nanoplatforms and cascade processes for enhanced therapeutic outcomes.

Main Methods:

  • Summarizing and discussing the design of nanoplatforms with specific structures, compositions, and properties.
  • Analyzing the implementation of cascade processes using tumor microenvironment (TME) resources and exogenous energy.
  • Highlighting the generation of therapeutic species and enhanced tumoricidal effects.

Main Results:

  • Nanoplatform-based cascade engineering significantly improves anti-tumor efficacy.
  • This strategy offers enhanced controllability, specificity, and effectiveness compared to single-component therapies.
  • Smart nanoplatforms can be triggered by endogenous or exogenous stimuli for targeted therapy.

Conclusions:

  • Nanoplatform-based cascade engineering holds immense potential for advancing cancer therapy.
  • Further development is needed to meet personalized treatment demands.
  • This strategy provides a promising avenue for more effective and less toxic cancer treatments.