Related Experiment Video
Updated: Dec 3, 2025

Anionic Polymerization of an Amphiphilic Copolymer for Preparation of Block Copolymer Micelles Stabilized by π-π Stacking Interactions
Published on: October 10, 2016
Aggregation of a double hydrophilic block glycopolymer: the effect of block polymer ratio
Takahiro Oh1, Yu Hoshino, Yoshiko Miura
1Department of Chemical Engineering, Kyushu University, 744 Motooka, Nishiku, Fukuoka 819-0395, Japan. miuray@chem-eng.kyushu-u.ac.jp.
Abstract:
Double hydrophilic block glycopolymers (DHBGs) composed of glycopolymers and polyethylene glycol (PEG) aggregate in aqueous solution. However, there are no guidelines to direct and design DHBG aggregation. Herein, we investigated the effect of the ratio of glycopolymer length to PEG length on the structure, and report that structure size could be influenced by the block polymer ratio. Nine kinds of DHBG with different glycopolymers and PEG lengths were synthesized via reversible addition-fragmentation chain transfer (RAFT) polymerization. The aggregation capability of DHBG was investigated by transmission electron microscopy (TEM) and dynamic light scattering (DLS). In all cases, the DHBGs formed the spherical structures, even when the PEG and glycopolymer lengths were quite different. The size of the structure was controlled by the ratio of the PEG length to the glycopolymer length. The aggregation of the DHBGs was induced by hydrogen bonding between the sugar moieties. The aggregation of the DHBG was affected by temperature and concentration.
More Related Videos
09:02Using Polystyrene-block-polyacrylic acid-coated Metal Nanoparticles as Monomers for Their Homo- and Co-polymerization
Published on: July 9, 2015
11:42Synthesis of Monodisperse Cylindrical Nanoparticles via Crystallization-driven Self-assembly of Biodegradable Block Copolymers
Published on: June 20, 2019
Related Concept Videos
Characteristics and Nomenclature of Copolymers
Molecular Weight of Step-Growth Polymers
As the step-growth polymerization involves step-wise condensation of monomers, the molecular weight also builds up eventually. Consequently, high molecular weight polymers are obtained at the late stages of the polymerization, where 99% of monomers have been consumed.
The extent of the...
Step-Growth Polymerization: Overview
Many natural and synthetic polymers are produced by...