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Urological complications in 600 consecutive renal transplants
A Jaskowski1, R M Jones, J A Murie
1Nuffield Department of Surgery, University of Oxford, Churchill Hospital, UK.
The British Journal of Surgery
|October 1, 1987
Summary
Urological complications after renal transplantation, including ureteric obstruction and urine leakage, occurred in 7% of patients. Modern surgical techniques and reduced immunosuppression have lowered this rate to 1-2%.
Area of Science:
- Urology
- Transplantation Surgery
Background:
- Urological complications are a significant concern following renal transplantation.
- The Leadbetter-Politano ureteroneocystostomy technique and Foley catheter drainage were standard procedures.
Purpose of the Study:
- To assess the incidence and causes of urological complications in a large series of renal transplant operations.
- To identify predisposing factors for these complications.
- To evaluate the impact of surgical technique and immunosuppression on complication rates.
Main Methods:
- Retrospective analysis of 600 consecutive renal transplant operations in 491 patients.
- Detailed review of urological complications, including ureteric obstruction and urine leakage.
- Identification of anatomical predisposing factors and causes of complications.
Main Results:
- Overall, 7% of patients experienced urological complications.
- Ureteric obstruction occurred in 26 patients (27 episodes) with various causes and locations.
- Urine leakage occurred in 18 patients (21 episodes), with anatomical factors present in 59%.
Conclusions:
- The incidence of urological complications has decreased due to improved surgical techniques and reduced steroid dosage for immunosuppression.
- Current rates of urological complications after renal transplantation are between 1% and 2%.
- The Leadbetter-Politano technique and optimized immunosuppression contribute to favorable outcomes.