Related Experiment Video
Updated: Dec 3, 2025
06:46
Simultaneous Laryngopharyngeal and Conventional Esophageal pH Monitoring
Published on: December 14, 2020
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[Gastro-oesophageal reflux disease-update 2021]
J Labenz1, D-P Borkenstein2, M Müller2
1Innere Medizin, Diakonie Klinikum Jung-Stilling Krankenhaus, Wichernstr. 40, 57074, Siegen, Deutschland. info@joachim-labenz.de.
Der Internist
|October 28, 2020
Summary
Gastro-oesophageal reflux disease (GORD) diagnosis can be challenging. Treatment involves proton pump inhibitors (PPIs), with options for optimization or antireflux procedures if needed.
Area of Science:
- Gastroenterology
- Digestive Diseases
Background:
- Gastro-oesophageal reflux disease (GORD) is highly prevalent.
- It is characterized by troublesome symptoms or esophageal lesions due to gastric reflux.
- A definitive diagnostic gold standard for GORD is currently lacking.
Purpose of the Study:
- To outline diagnostic approaches for GORD.
- To discuss current therapeutic strategies for GORD management.
- To highlight the role of advanced diagnostic tools and treatment options.
Main Methods:
- Review of patient history and endoscopic findings.
- Utilizing pH-impedance monitoring for reflux evaluation.
- Incorporating high-resolution manometry for pathophysiological insights.
Main Results:
- Diagnosis relies on a combination of clinical history, endoscopy, and pH-impedance monitoring.
- High-resolution manometry aids in identifying motility disorders.
- Proton pump inhibitors (PPIs) are the primary pharmacotherapy.
Conclusions:
- Accurate GORD diagnosis requires integrating multiple diagnostic modalities.
- Treatment optimization includes adjusting PPI dosage, combination therapy, or considering antireflux procedures.
- Patient-specific pathophysiological data guides treatment decisions.
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