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BSER audiometry in haemodialysis patients
G Magliulo1, M Gagliardi, G Ralli
1ENT Department, University La Sapienza, Rome, Italy.
Clinical Otolaryngology and Allied Sciences
|August 1, 1987
Summary
This study investigated brain stem evoked responses in chronic renal failure patients undergoing hemodialysis and after kidney transplantation. Hemodialysis offered temporary improvements, while transplantation normalized brain stem conduction, indicating its utility in monitoring uremic central nervous system status.
Area of Science:
- Neuroscience
- Nephrology
Background:
- Chronic renal failure (CRF) leads to metabolic abnormalities affecting the central nervous system.
- Uremia can cause neurological dysfunction, impacting brain stem conduction.
Purpose of the Study:
- To evaluate brain stem evoked responses (BSER) in patients with CRF undergoing hemodialysis.
- To assess the impact of hemodialysis and successful renal transplantation on BSER.
- To explore the utility of evoked potentials in monitoring neurological status in uremic patients.
Main Methods:
- Brain stem evoked responses were measured in 20 patients with CRF undergoing hemodialysis.
- BSER were also analyzed in 5 successful renal transplant recipients.
- Changes in BSER were tracked before, during, and after dialysis, and post-transplantation.
Main Results:
- Before hemodialysis, 30% of CRF patients exhibited abnormal BSER.
- Hemodialysis temporarily improved brain stem conduction, with effects diminishing within 24 hours.
- Successful renal transplantation led to complete normalization of previously abnormal BSER.
Conclusions:
- Hemodialysis provides transient improvements in brain stem conduction in uremic patients.
- Successful renal transplantation effectively reverses uremic-induced abnormalities in brain stem conduction.
- Evoked potentials are valuable tools for monitoring central nervous system function in chronic renal failure.