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Updated: Jun 29, 2026

Prehospital Thrombolysis: A Manual from Berlin
Published on: November 26, 2013
Performance evolution over 645 acute stroke thrombectomies in a public Brazilian healthcare institution
Luís H de Castro-Afonso1, Guilherme S Nakiri1, Vitor R Fornazari1
1Division of Interventional Neuroradiology, Department of Radiology, Hematology and Oncology, Ribeirão Preto Medical School, University of São Paulo, São Paulo, Brazil.
Background:
Assessment of the impact of the thrombectomy learning curve on clinical outcomes is essential for developing healthcare system protocols.
Aims:
The aim of this study was to assess the effect of thrombectomy case volume on procedural and clinical outcomes in a Brazilian registry.
Methods:
A total of 645 patients with acute ischemic stroke treated by thrombectomy were included in the analysis. Patients were divided into two groups regarding the period of treatment: the early period group and the late period group.
Results:
In the adjusted analysis, treatment in the late period was an independent predictor of recanalization (odds ratio 1.91, 95% CI 1.28-2.86) and excellent neurologic outcomes at three months (odds ratio 1.77, 95% CI 1.04-3.01). Treatment in the late period had no significant association with mortality (odds ratio 0.88, 95% CI 0.55-1.41).
Conclusions:
An increase in thrombectomy case volume for the treatment of AIS over time was an independent predictor of recanalization and excellent neurologic outcome.
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