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Degos disease: a case report and review of the literature
Santosh Tummidi1, Prabhakaran Nagendran2, Swaroopa Gedela3
1Department of Pathology, All India Institute of Medical Sciences, Mangalagiri, Andhra Pradesh, India. born_vss@yahoo.co.in.
Background:
Degos disease is a very rare syndrome with multisystem vasculopathy of unknown cause. It can affect the skin, gastrointestinal tract, and central nervous system. However, other organs such as the kidney, lungs, pleura, and liver can also be involved.
Case Presentation:
A 35-year-old Hindu woman presented to our dermatology outpatient department with complaints of depigmented painful lesions. A skin punch biopsy taken from the porcelain white atrophic papules which revealed features of Degos disease.
Conclusion:
The diagnosis of Degos disease is usually based on the presence of the pathognomonic skin lesions and a tissue biopsy demonstrating a wedge-shaped area of necrosis with thrombotic occlusion of the small arterioles. No specific treatment is currently available for this disease.
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