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Possible Oncogenic Viruses Associated with Lung Cancer
Yan Hu1, Siying Ren2, Yu He1
1Department of Thoracic Surgery, The Thoracic Surgery Research Room, Second Xiangya Hospital, Central South University, Changsha 410011, People's Republic of China.
Oncotargets and Therapy
|October 29, 2020
Summary
While tobacco smoking is a primary cause of lung cancer, not all smokers develop the disease. This review explores the potential role of oncogenic viruses as cofactors in lung cancer development.
Area of Science:
- Oncology
- Virology
- Cancer Research
Background:
- Lung cancer is the leading cause of cancer mortality globally.
- Tobacco smoking is the primary risk factor, but only a fraction of smokers develop the disease.
- This suggests other cofactors, such as viruses, may be involved in lung carcinogenesis.
Purpose of the Study:
- To review potential oncogenic viruses associated with lung cancer.
- To investigate the unclear role of viruses in lung cancer etiology.
Main Methods:
- Literature review of scientific articles.
- Analysis of studies on virus-associated cancers.
- Synthesis of evidence regarding viral involvement in lung carcinogenesis.
Main Results:
- The review identifies several viruses with potential oncogenic properties.
- Evidence suggests a possible link between specific viruses and lung cancer development in certain populations.
- The precise mechanisms of viral oncogenesis in lung cancer require further investigation.
Conclusions:
- Viruses may act as cofactors in lung cancer development alongside smoking.
- Further research is needed to elucidate the specific roles and mechanisms of oncogenic viruses in lung cancer.
- Understanding these viral roles could lead to new prevention and treatment strategies.
Keywords:
Epstein–Barr virusJohn Cunningham virusMerkel cell polyomavirushuman papillomavirusjaagsiekte sheep viruslung canceroncogenic virusMore Related Videos
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