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Current Options in the Treatment of COVID-19: A Review
Azadeh Teimury1, Elahe Mahmoodi Khaledi1
1Department of Cell and Molecular Biology, Faculty of Chemistry, University of Kashan, Kashan, Iran.
Insights
This review examines common drugs used for COVID-19, including antivirals and immune modulators. It compares their effectiveness and side effects, offering insights for researchers on SARS-CoV-2 treatments.
Area of Science:
- Virology
- Infectious Diseases
- Pharmacology
Background:
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic.
- No specific vaccines or drugs were initially available for COVID-19.
- Existing treatments from past viral epidemics were repurposed.
Purpose of the Study:
- To review and analyze widely used drugs for treating COVID-19.
- To compare the efficacy and safety of various drug classes.
- To provide valuable information for researchers on SARS-CoV-2 therapies.
Main Methods:
- Literature review of existing studies on COVID-19 treatments.
- Collection of data on antivirals, antibiotics, immune modulators, and anticoagulants.
- Analysis of drug efficacy in both laboratory conditions and clinical settings.
Main Results:
- Evaluated the pros and cons of using different drug categories for COVID-19.
- Compared the outcomes of various treatment strategies, both standalone and in combination.
- Identified key findings regarding the effectiveness of repurposed drugs.
Conclusions:
- Summarized the current landscape of COVID-19 pharmacotherapy.
- Highlighted the importance of continued research into effective SARS-CoV-2 treatments.
- Provided a comparative overview to guide future therapeutic decisions.
Abstract:
Novel Coronavirus, also known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), emerged in December 2019 in China and spread rapidly all around the world infecting many people. To date, no specific vaccines and drugs have been developed for this disease. Also, due to the COVID-19 pandemic and high prevalence of the infected patients, the drugs and the therapies of other past viral epidemics have been used for this disease. Many studies have been performed on the specific treatments to find whether or not they are effective on COVID-19 patients. In this review, we collected information about the most widely used drugs to treat COVID-19 (coronavirus disease 2019) belonging to groups of antivirals, antibiotics, immune modulators, and anticoagulants. Some of these compounds and drugs were used directly by inpatients, so researchers have examined others in laboratory conditions. This study considered the pros and cons of using these treatments separately and together and compared their results. By studying this review, we hope to provide useful information for researchers.
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